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Chemical Composition and Antibacterial Activity of the Essential Oil of Drimys granadensis L. f . Leaves from Colombia
Author(s) -
Gaviria Mauricio,
Quijano Clara,
Pino Jorge,
Madriñán Santiago
Publication year - 2011
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201000170
Subject(s) - essential oil , germacrene , chemistry , germacrene d , traditional medicine , botany , bacteria , composition (language) , chemical composition , food science , biology , organic chemistry , medicine , genetics , linguistics , philosophy
Drimys granadensis L. f ., a native plant from Colombia, has been included in the Vademecum de Plantas Medicinales de Colombia by the Instituto de Investigación de Recursos Biológicos Alexander von Humboldt , due to its widespread use in the folk medicine for the treatment of gastrointestinal ailments. The chemical composition of the essential oil of Drimys granadensis obtained by hydrodistillation of the leaves was analyzed by GC and GC/MS analyses. A total of 85 components were identified, with the major compounds germacrene D ( 1 , 14.7%), sclarene (9.5%), α ‐cadinol (7.3%), longiborneol acetate ( 2 , 6.3%), drimenol (4.2%), ( Z )‐ β ‐ocimene ( 3 , 4.2%), α ‐pinene ( 4 , 3.2%), and β ‐elemene ( 5 , 2.7%). The essential oil was also tested against eight bacteria using the KirbyBauer disk‐diffusion method. Most of the Gram ‐positive bacteria tested were susceptible to the D. granadensis essential oil, while the Gram ‐negative bacteria tested were not.