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Terpenes from the Soft Corals Litophyton arboreum and Sarcophyton ehrenbergi
Author(s) -
Shaker Kamel H.,
Müller Michael,
Ghani M. Abdel,
Dahse HansMartin,
Seifert Karlheinz
Publication year - 2010
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.201000016
Subject(s) - terpene , chemistry , botany , zoology , stereochemistry , biology
The new cembrane diterpene (3 E ,11 E )‐cembra‐3,8(19),11,15‐tetraene‐7 α ‐ol ( 1 ), nephthenol ( 2 ), and all‐ trans ‐peridinin ( 3 ) have been isolated from the soft coral Litophyton arboreum. The tetraterpene 3 , (+)‐7,8‐epoxy‐7,8‐dihydrocembrene C ( 4 ), emblide ( 5 ), sarcophytoxide ( 6 ), sarcoglaucol‐16‐one ( 7 ), guajacophine ( 8 ), and 1,4‐peroxymuurol‐5‐ene ( 9 ) have been obtained from the soft coral Sarcophyton ehrenbergi. The compounds were characterized primarily by NMR spectroscopy. Some of the terpenes were tested for their antiproliferative activity against the cell lines HUVEC and K‐562 and for cytotoxicity against the cell line HeLa, and they showed moderate activities.