New Biological Functions and Applications of High‐Molecular‐Mass Poly‐ γ ‐glutamic Acid | Zendy

Poo Haryoung | Zendy; Park Chung | Zendy; Kwak MiSun | Zendy; Choi DooYeol | Zendy; Hong SeungPyo | Zendy; Lee IlHan | Zendy; Lim Yong Taik | Zendy; Choi Young Ki | Zendy; Bae SunRyang | Zendy; Uyama Hiroshi | Zendy; Kim ChulJoong | Zendy; Sung MoonHee | Zendy

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New Biological Functions and Applications of High‐Molecular‐Mass Poly‐ γ ‐glutamic Acid

Author(s) -

Poo Haryoung,

Park Chung,

Kwak MiSun,

Choi DooYeol,

Hong SeungPyo,

Lee IlHan,

Lim Yong Taik,

Choi Young Ki,

Bae SunRyang,

Uyama Hiroshi,

Kim ChulJoong,

Sung MoonHee

Publication year - 2010

Publication title -

chemistry and biodiversity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.427

H-Index - 70

eISSN - 1612-1880

pISSN - 1612-1872

DOI - 10.1002/cbdv.200900283

Subject(s) - chemistry , glutamic acid , computational biology , biophysics , combinatorial chemistry , nanotechnology , biochemistry , amino acid , biology , materials science

Ultra‐high‐molecular‐weight poly‐ γ ‐glutamic acid ( γ ‐PGA) is a most promising biodegradable polymer that is produced by Bacillus subtilis (chungkookjang). Attractive properties of γ ‐PGA are that it is water soluble, anionic, biodegradable, and edible. Development of γ ‐PGA has pursued in terms of cosmetics/skin care, bone care, nanoparticle for drug delivery system, hydrogel, and so on. Very recently, our research has shown that γ ‐PGA can be used as an immune‐stimulating agent, especially at high molecular weight. This review presents the synthesis and production of high‐molecular‐weight γ ‐PGA and its various applications in industrial fields.

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