Prenylated Benzophenone Peroxide Derivatives from  Hypericum sampsonii | Zendy

Xiao Zhi Yong | Zendy; Zeng Yi Han | Zendy; Mu Qing | Zendy; Shiu Winnie Ka Po | Zendy; Gibbons Simon | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Prenylated Benzophenone Peroxide Derivatives from Hypericum sampsonii

Author(s) -

Xiao Zhi Yong,

Zeng Yi Han,

Mu Qing,

Shiu Winnie Ka Po,

Gibbons Simon

Publication year - 2010

Publication title -

chemistry and biodiversity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.427

H-Index - 70

eISSN - 1612-1880

pISSN - 1612-1872

DOI - 10.1002/cbdv.200900247

Subject(s) - benzophenone , chemistry , peroxide , moiety , staphylococcus aureus , prenylation , stereochemistry , organic chemistry , bacteria , biology , genetics , enzyme

Two new prenylated benzophenone peroxide derivatives, peroxysampsones A and B ( 1 and 2 , resp.), together with a known compound, plukenetione C ( 3 ), were isolated from the roots of the Chinese medicinal plant Hypericum sampsonii , and their structures were elucidated by detailed spectral analysis. These compounds are the unusual peroxides of polyprenylated benzophenone derivatives, containing the unique caged moiety of 4,5‐dioxatetracyclo[9.3.1.1 9,13 .0 1,7 ]hexadecane‐12,14,15‐trione. In the biological test, peroxysampsone A ( 1 ) showed comparable activity with norfloxacin against a NorA over‐expressing multidrug‐resistant (MDR) strain of Staphylococcus aureus SA‐1199B.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research