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Triplex‐Stabilizing Properties of Parallel Clamps Carrying LNA Derivatives at the Hoogsteen Strand
Author(s) -
Alvira Margarita,
Eritja Ramon
Publication year - 2010
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200900230
Subject(s) - chemistry , biophysics , stereochemistry , biology
DNA Parallel clamps with a polypurine strand linked to a polypyrimidine Hoogsteen strand containing locked nucleic acids bind their corresponding polypyrimidine targets with high affinity.