Four New Sesquiterpenes from  Curcuma wenyujin  and Their Inhibitory Effects on Nitric‐Oxide Production | Zendy

Lou Yan | Zendy; Zhao Feng | Zendy; He Hao | Zendy; Peng KaiFeng | Zendy; Chen LiXia | Zendy; Qiu Feng | Zendy

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Four New Sesquiterpenes from Curcuma wenyujin and Their Inhibitory Effects on Nitric‐Oxide Production

Author(s) -

Lou Yan,

Zhao Feng,

He Hao,

Peng KaiFeng,

Chen LiXia,

Qiu Feng

Publication year - 2010

Publication title -

chemistry and biodiversity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.427

H-Index - 70

eISSN - 1612-1880

pISSN - 1612-1872

DOI - 10.1002/cbdv.200900160

Subject(s) - sesquiterpene , nitric oxide , chemistry , sesquiterpene lactone , stereochemistry , terpene , traditional medicine , organic chemistry , medicine

Four new sesquiterpenes including the novel sesquiterpene lactone (6 R )‐dehydroxysipanolinolide ( 1 ), two new eudesmane‐type sesquiterpenes, curcolide ( 2 ) and curcodione ( 3 ), and a new xanthane‐type sesquiterpene, curcumadionol ( 4 ), were isolated from Curcuma wenyujin Y. H. Chen et C. Ling , together with five known ones, 5 – 9 . The structures of the new compounds were elucidated by spectroscopic methods. The inhibitory effects of compounds 1 – 9 on nitric‐oxide production in lipopolysaccaride‐activated macrophages were evaluated.

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