Two New Furanoeremophilanes from  Senecio santelisis | Zendy

Arias Cassará María L. | Zendy; Borkosky Susana A. | Zendy; Sierra Manuel González | Zendy; Bardón Alicia | Zendy; Ybarra María I. | Zendy

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Two New Furanoeremophilanes from Senecio santelisis

Author(s) -

Arias Cassará María L.,

Borkosky Susana A.,

Sierra Manuel González,

Bardón Alicia,

Ybarra María I.

Publication year - 2010

Publication title -

chemistry and biodiversity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.427

H-Index - 70

eISSN - 1612-1880

pISSN - 1612-1872

DOI - 10.1002/cbdv.200900080

Subject(s) - chemistry , senecio , botany , biology

From an Argentine collection of Senecio santelisis Phil ., the new furanoeremophilanoids, (10 βH )‐6 β ‐acetoxy‐1 α ‐hydroxyfuranoeremophilan‐9‐one ( 1 ) and (10 βH )‐1 α ‐hydroxy‐6 β ‐(propanoyloxy)furanoeremophilan‐9‐one ( 2 ), together with the known (10 αH )‐6 β ‐acetoxy‐1 α ‐hydroxyfuranoeremophilan‐9‐one ( 3 ), (10 αH )‐1 α ,6 β ‐diacetoxyfuranoeremophilan‐9‐one ( 4 ), and (10 αH )‐1 α ‐hydroxy‐6 β ‐(propanoyloxy)furanoeremophilan‐9‐one ( 5 ) were isolated. Their structures and relative configurations were established on the basis of spectroscopic analysis. CHCl 3 Extract and pure compounds were evaluated for their antifungal activity. Compound 5 exhibited remarkable mycelial growth inhibition against B. cinerea with an IC 50 value of 21.4 μg/ml.

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