Premium
Synthesis, Characterization, and Antifungal Activity of Boron‐Containing Thiosemicarbazones
Author(s) -
Hicks Justin W.,
Kyle Christian B.,
Vogels Christopher M.,
Wheaton Susan L.,
Baerlocher Felix J.,
Decken Andreas,
Westcott Stephen A.
Publication year - 2008
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200890206
Subject(s) - chemistry , antifungal , boron , boronic acid , combinatorial chemistry , organic chemistry , semicarbazone , stereochemistry , microbiology and biotechnology , biology
Addition of thiosemicarbazide, 4‐allylthiosemicarbazide, and 4‐phenylthiosemicarbazide to (formylphenyl)boronic acids affords a series of thiosemicarbazones containing boronic acids. Addition of 2‐formylphenylboronic acid to the thiosemicarbazides gave the corresponding cyclic 2,3,1‐benzodiazaborines. All new compounds have been investigated for potential antifungal activity.