Synthesis, Characterization, and Antifungal Activity of Boron‐Containing Thiosemicarbazones | Zendy

Hicks Justin W. | Zendy; Kyle Christian B. | Zendy; Vogels Christopher M. | Zendy; Wheaton Susan L. | Zendy; Baerlocher Felix J. | Zendy; Decken Andreas | Zendy; Westcott Stephen A. | Zendy

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Synthesis, Characterization, and Antifungal Activity of Boron‐Containing Thiosemicarbazones

Author(s) -

Hicks Justin W.,

Kyle Christian B.,

Vogels Christopher M.,

Wheaton Susan L.,

Baerlocher Felix J.,

Decken Andreas,

Westcott Stephen A.

Publication year - 2008

Publication title -

chemistry and biodiversity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.427

H-Index - 70

eISSN - 1612-1880

pISSN - 1612-1872

DOI - 10.1002/cbdv.200890206

Subject(s) - chemistry , antifungal , boron , boronic acid , combinatorial chemistry , organic chemistry , semicarbazone , stereochemistry , microbiology and biotechnology , biology

Addition of thiosemicarbazide, 4‐allylthiosemicarbazide, and 4‐phenylthiosemicarbazide to (formylphenyl)boronic acids affords a series of thiosemicarbazones containing boronic acids. Addition of 2‐formylphenylboronic acid to the thiosemicarbazides gave the corresponding cyclic 2,3,1‐benzodiazaborines. All new compounds have been investigated for potential antifungal activity.

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