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New Pentacyclic Triterpenes from Gypsophila oldhamiana and Their Biological Evaluation as Glycogen Phosphorylase Inhibitors
Author(s) -
Luo JianGuang,
Liu Jun,
Kong LingYi
Publication year - 2008
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200890071
Subject(s) - terpene , glycogen phosphorylase , chemistry , stereochemistry , biochemistry , glycogen
The three new pentacyclic triterpenes 1 – 3 were isolated and elucidated from the roots of Gypsophila oldhamiana , together with seven known triterpenes ( 4 – 10 ). These triterpenes were evaluated for their glycogen phosphorylase inhibitory activity and preliminary structure–activity trends are suggested.