Cycloartane Triterpenes from Dikamali, the Gum Resin of  Gardenia gummifera  and  Gardenia lucida | Zendy

Kunert Olaf | Zendy; Sreekanth Gandhe | Zendy; Babu Gummadi Sreedhar | Zendy; Rao Belvotagi Venkat Rao Adavi | Zendy; Radhakishan Marupaka | Zendy; Kumar Bobbala Ravi | Zendy; Saf Robert | Zendy; Rao Achanta Venkata Narasimha Appa | Zendy; Schühly Wolfgang | Zendy

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Cycloartane Triterpenes from Dikamali, the Gum Resin of Gardenia gummifera and Gardenia lucida

Author(s) -

Kunert Olaf,

Sreekanth Gandhe,

Babu Gummadi Sreedhar,

Rao Belvotagi Venkat Rao Adavi,

Radhakishan Marupaka,

Kumar Bobbala Ravi,

Saf Robert,

Rao Achanta Venkata Narasimha Appa,

Schühly Wolfgang

Publication year - 2009

Publication title -

chemistry and biodiversity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.427

H-Index - 70

eISSN - 1612-1880

pISSN - 1612-1872

DOI - 10.1002/cbdv.200800339

Subject(s) - terpene , gardenia , chemistry , rubiaceae , stereochemistry , candida albicans , moiety , traditional medicine , staphylococcus aureus , flavonoid , botany , bacteria , organic chemistry , biology , traditional chinese medicine , genetics , medicine , alternative medicine , pathology , antioxidant

We report on the chemical investigation of dikamali gum, which is the resin of Gardenia gummifera and G. lucida (Rubiaceae). Six new cycloartane triterpenes, dikamaliartanes A–F ( 1 – 6 , resp.), together with a known flavonoid ( 7 ), were isolated and identified by NMR spectroscopy. All six cycloartanes are characterized by an open A ‐ring with a free COOH group at C(3). In four of them, the C‐atoms C(23)–C(27) form a 4‐methylfuran‐2‐yl moiety. Bacterial assays using Staphylococcus aureus, Candida albicans , and Mycobacteria have been carried out but did not reveal significant activity.

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