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New (9 βH )‐Lanostanes and Lanostanes from Mikania aff. jeffreyi (Asteraceae)
Author(s) -
Mendes Carla C.,
Sandes Luciana Q.,
Cruz Frederico G.,
Roque Nídia F.
Publication year - 2009
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200800269
Subject(s) - asteraceae , terpene , lanostane , diene , chemistry , stereochemistry , triterpene , botany , organic chemistry , biology , medicine , alternative medicine , natural rubber , pathology
Four new (9 βH )‐lanostanes, i.e. , (9 βH )‐3 β ‐acetoxylanosta‐7,24‐diene, (9 βH )‐3‐oxolanosta‐7,24‐diene, (9 βH ,24 R )‐3 β ‐acetoxy‐24‐hydroxylanosta‐7,25‐diene, and (9 βH ,24 S )‐3 β ‐acetoxy‐24‐hydroxylanosta‐7,25‐diene, two new lanostanes, i.e. , (24 R )‐3 β ‐acetoxy‐24‐hydroxylanosta‐8,25‐diene and (24 S )‐3 β ‐acetoxy‐24‐hydroxylanosta‐8,25‐diene, and two known lanostanes, i.e. , 3 β ‐acetoxylanosta‐8,24‐diene and 3‐oxolanosta‐8,24‐diene, were obtained from a new Mikania species (Asteraceae) besides pentacyclic triterpenes, steroids, and diterpenes. The structures of the compounds were determined by spectroscopic methods. This is the second study about acetyl‐lanosterols from higher plants. Moreover, (9 βH )‐lanostanes are very rare metabolites from dicotyledone angiosperms. The occurrence of these terpenes together in the same plant makes the species a good source for lanostane‐ and (9 βH )‐lanostane‐biosynthesis studies.