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New Nitrogen‐Containing Sesquiterpenoids from the Taiwanese Soft Coral Cespitularia taeniata May
Author(s) -
Cheng YuanBin,
Chen ChingYeu,
Kuo YaoHaur,
Shen YaChing
Publication year - 2009
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200800195
Subject(s) - sesquiterpene , chemistry , coral , sesquiterpene lactone , stereochemistry , terpenoid , terpene , biology , ecology
Abstract Chemical investigation of the EtOH extract of the soft coral Cespitularia taeniata May collected in Taiwan has resulted in the isolation of two new sesquiterpene lactams, taenialactams A and B ( 1 and 2 , resp.), and a new sesquiterpene lactone, taenialactone A ( 3 ), together with 8 β ‐methoxyatractylenolide ( 4 ) and atractylenolactam ( 5 ). The structures of these compounds were determined on the basis of spectroscopic analyses. The in vitro cytotoxic activities of the isolated metabolites were tested against KB, Daoy, and WiDr cell lines. A biogenetic pathway for these novel compounds was proposed.