Premium
Two Unusual Naphthalene‐Containing Compounds from a Freshwater Fungus YMF 1.01029
Author(s) -
Dong JinYan,
Song HongChuan,
Li JianHua,
Wang ChunRen,
Sun Rong,
Tang YuShu,
Shen KaiZe,
Wang Le,
Wang LiMei,
Zhou YongPing,
Li Lei,
Zhang KeQin
Publication year - 2009
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200800028
Subject(s) - naphthalene , fungus , chemistry , antifungal , stereochemistry , diene , organic chemistry , botany , microbiology and biotechnology , biology , natural rubber
Two novel naphthalene‐containing compounds, colelomycerones A and B ( 1 and 2 , resp.), and three known metabolites, including preussomerin D ( 3 ), (2 RS ,2′ SR ,3′ E ,3 SR ,4 E ,8 E )‐1‐ O ‐( β ‐ D ‐glucopyranosyl)‐3‐hydroxy‐2‐[(2‐hydroxyoctadec‐3‐enoyl)amino]‐9‐methyloctadeca‐4,8‐diene ( 4 ), and 3 β ‐hydroxy‐5 α ,8 α ‐epidioxyergosta‐6,22‐diene ( 5 ), were isolated from the culture broth of an unidentified freshwater water fungus YMF 1.01029. This fungus was collected from a decaying branch of an unidentified tree near Lake Fuxian in Yunnan Province, China. The structures of these five compounds were determined on the basis of their spectroscopic and mass‐spectrometric data. Colelomycerones A and B ( 1 and 2 , resp.) represent unprecendented examples of naphthalene‐1,2‐diones with novel cyclic acetals. Compounds 1 – 3 showed noticeable antifungal and antibacterial activities.