New Lipoxygenase‐Inhibiting Constituents from  Calligonum polygonoides | Zendy

Yawer Mirza Arfan | Zendy; Ahmed Ejaz | Zendy; Malik Abdul | Zendy; Ashraf Muhammad | Zendy; Rasool Muhammad Azam | Zendy; Afza Nighat | Zendy

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New Lipoxygenase‐Inhibiting Constituents from Calligonum polygonoides

Author(s) -

Yawer Mirza Arfan,

Ahmed Ejaz,

Malik Abdul,

Ashraf Muhammad,

Rasool Muhammad Azam,

Afza Nighat

Publication year - 2007

Publication title -

chemistry and biodiversity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.427

H-Index - 70

eISSN - 1612-1880

pISSN - 1612-1872

DOI - 10.1002/cbdv.200790137

Subject(s) - chemistry , ursolic acid , lipoxygenase , glucoside , stereochemistry , biochemistry , chromatography , enzyme , medicine , alternative medicine , pathology

Calligonolides A ( 1 ) and B ( 2 ), two new butanolides, and a new steroidal ester, 3 , have been isolated from the whole plant of Calligonum polygonoides , together with four known compounds, tetracosan‐4‐olide, β ‐sitosterol and its glucoside, and ursolic acid. Their structures were elucidated by spectroscopic and mass‐spectrometric studies. Compounds 1 – 3 showed moderate inhibitory potential against lipoxygenase from soybean.

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