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New Lipoxygenase‐Inhibiting Constituents from Calligonum polygonoides
Author(s) -
Yawer Mirza Arfan,
Ahmed Ejaz,
Malik Abdul,
Ashraf Muhammad,
Rasool Muhammad Azam,
Afza Nighat
Publication year - 2007
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200790137
Subject(s) - chemistry , ursolic acid , lipoxygenase , glucoside , stereochemistry , biochemistry , chromatography , enzyme , medicine , alternative medicine , pathology
Calligonolides A ( 1 ) and B ( 2 ), two new butanolides, and a new steroidal ester, 3 , have been isolated from the whole plant of Calligonum polygonoides , together with four known compounds, tetracosan‐4‐olide, β ‐sitosterol and its glucoside, and ursolic acid. Their structures were elucidated by spectroscopic and mass‐spectrometric studies. Compounds 1 – 3 showed moderate inhibitory potential against lipoxygenase from soybean.