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X‐Ray Crystal Structure and Antioxidant Activity of Salidroside, a Phenylethanoid Glycoside
Author(s) -
Yu Peizhong,
Hu Changqi,
Meehan Edward J.,
Chen Liqing
Publication year - 2007
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200790043
Subject(s) - chemistry , salidroside , phenylethanoid , pyrogallol , tyrosol , glycoside , aglycone , superoxide , antioxidant , chemiluminescence , phenol , stereochemistry , organic chemistry , chromatography , enzyme
The X‐ray single‐crystal structure of natural salidroside (=2‐(4‐hydroxyphenyl)ethyl β ‐ D ‐glucopyranoside; 1 ), isolated from Cistanche deserticola , is reported for the first time, as well as its absolute configuration. The radical‐scavenging activity of 1 towards the superoxide radical anion (O $_{2}^{{\cdot} -}$ ) was determined experimentally by chemiluminescence measurements of the pyrogallol–luminol system, and compared to that of the corresponding aglycone, i.e. , tyrosol (=4‐(2‐hydroxyethyl)phenol; 2 ).