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Three New Triterpenoids from Potentilla multicaulis
Author(s) -
Li PingLin,
Lin ChangJun,
Zhang ZhanXin,
Jia ZhongJian
Publication year - 2007
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200790002
Subject(s) - chemistry , triterpenoid , stereochemistry , cytotoxic t cell , terpene , two dimensional nuclear magnetic resonance spectroscopy , biochemistry , in vitro
Abstract Three new triterpenoids, 19‐hydroxy‐2,3‐secours‐12‐ene‐2,3,28‐trioic acid 3‐ methyl ester ( 1 ), 19‐hydroxy‐1‐oxo‐2‐nor‐2,3‐secours‐12‐ene‐3,28‐dioic acid ( 2 ), and (3 β ,18 α ,19 α )‐3,28‐dihydroxy‐20,28‐epoxyursan‐24‐oic acid ( 3 ), were isolated from the roots of Potentilla multicaulis. Their structures were elucidated on the basis of spectroscopic methods (IR, HR‐ESI‐MS, and 1D‐ and 2D‐NMR). Compound 2b exhibited moderate cytotoxic activity against human promyelocytic leukemia (HL‐60) cells.