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Five New Iridoids from Patrinia rupestris
Author(s) -
Yang XiuPing,
Li ErWei,
Zhang Qi,
Yuan ChengShan,
Jia ZhongJian
Publication year - 2006
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200690078
Subject(s) - chemistry , bacillus subtilis , staphylococcus aureus , escherichia coli , stereochemistry , traditional medicine , bacteria , biochemistry , biology , medicine , genetics , gene
Five new iridoids, namely rupesin A–E ( 1 – 5 , resp.), together with six known iridoids, 6 – 11 , were isolated from the roots of Patrinia rupestris. Their structures were elucidated by spectroscopic methods including IR, UV, MS, and 1D‐ and 2D‐NMR experiments, and comparison with data of known analogues. Compounds 4 and 11 , compounds 1, 2, 5, 6, 8, 9 , and 10 , and compounds 3, 4 , and 8 showed significant antibacterial activities against Bacillus subtilis, Escherichia coli , and Staphylococcus aureus , respectively.