A Homo‐Isoflavonoid and a Cytotoxic Saponin from Dracaena draco

Two new compounds, dracol (=(3 R )‐2,3‐dihydro‐3,5‐dihydroxy‐7‐methoxy‐3‐[(4‐methoxyphenyl)methyl]‐8‐methyl‐4 H ‐[1]benzopyran‐4‐one; 1 ) and icodeside (=(1 β ,3 β ,23 S ,24 S )‐3,23‐dihydroxy‐1‐{[2‐ O ‐(2,3,4‐tri‐ O ‐acetyl‐ α ‐ L ‐rhamnopyranosyl)‐α‐ L ‐arabinopyranosyl]oxy}spirosta‐5,25(27)‐dien‐24‐yl α ‐ L ‐arabinopyranoside; 2 ), were isolated from the EtOH extract of the leaves of Dracaena draco , together with 17 known constituents. The structures of 1 and 2 were elucidated by in‐depth spectroscopic analysis, and those of the known compounds were identified by comparison of their NMR and MS data with those reported in the literature. Icodeside ( 2 ) showed moderate cytotoxicity against human HL‐60 and A‐431 cells ( Table 3 ).