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Antifungal Bis[bibenzyls] from the Chinese Liverwort Marchantia polymorpha L.
Author(s) -
Niu Chong,
Qu JianBo,
Lou HongXiang
Publication year - 2006
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200690004
Subject(s) - bibenzyl , antifungal , chemistry , marchantia polymorpha , candida albicans , bioassay , isolation (microbiology) , stereochemistry , microbiology and biotechnology , biology , biochemistry , genetics , gene
Bioassay‐guided separation of the antifungal constituents of the Chinese liverwort Marchantia polymorpha L. (Marchantiaceae) led to the isolation of seven bis[bibenzyl]‐type macrocycles. On the basis of NMR and MS analyses, the three new compounds plagiochin E ( 1 ), 13,13′‐ O ‐isoproylidenericcardin D ( 4 ), and riccardin H ( 7 ) were identified, together with four known compounds: marchantin E ( 2 ), neomarchantin A ( 3 ), marchantin A ( 5 ), and marchantin B ( 6 ). Their antifungal activities against Candida albicans were determined by TLC bioautography.