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Radical‐Scavenging Activities of New Hydroxylated Ursane Triterpenes from cv. Annurca Apples
Author(s) -
D'Abrosca Brigida,
Fiorentino Antonio,
Monaco Pietro,
Pacifico Severina
Publication year - 2005
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200590072
Subject(s) - chemistry , terpene , scavenging , triterpene , organic chemistry , food science , antioxidant , medicine , alternative medicine , pathology
Two new ursolic acid triterpene derivatives, compounds 2 and 3 , have been isolated from cv. Annurca apple fruit, a high‐quality apple variety widely cultivated in southern Italy, together with the known 2‐oxopomolic acid ( 1 ). The new compounds were identified by means of different spectroscopic techniques as 3‐ epi ‐2‐oxopomolic acid (=(3 α )‐3,19‐dihydroxy‐2‐oxours‐12‐en‐28‐oic acid; 2 ) and (1 α )‐1‐hydroxy‐3‐oxours‐12‐en‐28‐oic acid ( 3 ). Compounds 1–3 were tested for their radical‐scavenging activities with the aid of a 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) assay ( Fig. 2 ). All three constituents showed activities similar to that of the reference antioxidant α ‐tocopherol (vitamin E).