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Chemical Constituents and Antioxidant Activity of Mallotus roxburghianus Leaves
Author(s) -
Rana Virendra S.,
Rawat Mohan S. M.,
Pant Geeta,
Nagatsu Akito
Publication year - 2005
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200590057
Subject(s) - betulinic acid , stigmasterol , chemistry , bergenin , chloroform , glucoside , antioxidant , traditional medicine , lupeol , coumaric acid , organic chemistry , chromatography , biology , medicine , genetics , alternative medicine , pathology
Mallotus roxburghianus is used in the traditional medicine in North‐Eastern India, but previously no work has been done on the identification of bioactive compounds. Two new compounds, 3‐(1‐ C ‐ β ‐ D ‐glucopyranosyl)‐2,6‐dihydroxy‐5‐methoxybenzoic acid ( 6 ) and 2,4,8,9,10‐pentahydroxy‐3,7‐dimethoxyanthracene‐6‐O‐ β ‐ D ‐rhamnopyranoside ( 7 ) together with β ‐sitosterol ( 1 ), stigmasterol ( 2 ), betulinic acid ( 3 ), 4‐hydroxybenzoic acid ( 4 ), β ‐sitosterol‐ β ‐ D ‐glucoside ( 5 ), and bergenin ( 8 ) were isolated and identified from the leaves of M. roxburghianus. The chloroform soluble portion of the alcoholic extract of leaf, and compounds 3, 6, 7 , and 8 exhibited encouraging antioxidant activities.