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Six New Constituents from the Roots of Erythrina variegata
Author(s) -
Tanaka Hitoshi,
Hirata Miyuki,
Etoh Hideo,
Sako Magoichi,
Sato Masaru,
Murata Jin,
Murata Hiroko,
Darnaedi Dedy,
Fukai Toshio
Publication year - 2004
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200490082
Subject(s) - erythrina , chemistry , staphylococcus aureus , stereochemistry , derivative (finance) , aryl , antibacterial activity , traditional medicine , organic chemistry , bacteria , biology , medicine , genetics , alkyl , financial economics , economics
Three new isoflavonoids, eryvarins M–O ( 1 – 3 ), two new 2‐arylbenzofurans, eryvarins P and Q ( 4 and 5 ), and a new 3‐aryl‐2,3‐dihydrobenzofuran, eryvarin R ( 6 ), together with three known compounds, were isolated from the roots of Erythrina variegata. The structures of these compounds were established by spectroscopic analysis. Eryvarin R ( 6 ) is an unusual 3‐aryl‐2,3‐dihydrobenzofuran derivative with a formyl (CHO) group. Eryvarin Q ( 5 ) showed potent antibacterial activity against methicillin‐resistant Staphylococcus aureus.