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DPPH Radical Scavenging Activity of Ten Natural p ‐Terphenyl Derivatives Obtained from Three Edible Mushrooms Indigenous to China
Author(s) -
Liu JiKai,
Hu Lin,
Dong ZeJun,
Hu Qun
Publication year - 2004
Publication title -
chemistry and biodiversity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.427
H-Index - 70
eISSN - 1612-1880
pISSN - 1612-1872
DOI - 10.1002/cbdv.200490050
Subject(s) - chemistry , scavenging , dpph , terphenyl , indigenous , mushroom , china , food science , organic chemistry , traditional medicine , antioxidant , ecology , medicine , political science , law , biology
The antioxidant activities of ten natural p ‐terphenyl derivatives, 1 – 10 , obtained from the fruiting bodies of three edible mushrooms ( Thelephora ganbajun, Thelephora aurantiotincta, Boletopsis grisea ) indigenous to China were evaluated in comparison with BHA (‘butylated hydroxyanisole’=(1,1‐dimethylethyl)‐4‐methoxyphenol) and α ‐tocopherol by the DPPH (‘1,1‐diphenyl‐2‐picrylhydrazyl’=2,2‐diphenyl‐1‐(2,4,6‐trinitrophenyl)hydrazyl) radical‐scavenging method. The compounds 1 – 3 showed significant antioxidant activity. The antioxidant activities of compounds 1 – 10 and reference compounds followed the order: 2 >BHA> 1 > 3 > α ‐tocopherol> 10 > 9 > 6 > 5 > 8 > 7 > 4 . The compound 2 exhibited the strongest radical‐scavenging activity with an EC 50 value of 0.07 ( EC 50 (BHA) 0.09; EC 50 ( α ‐tocopherol) 0.25).