Open AccessAssociation of marital status with stage and survival in patients with mycosis fungoides: A population‐based study
Author(s) -
Xing LingXiao,
Zhang Jing,
Shen Hui,
Tang XiaoLu,
He Lu,
Wu JiaZhu,
Li JianYong,
Miao Yi
Publication year - 2021
Publication title -
cancer medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.403
H-Index - 53
ISSN - 2045-7634
DOI - 10.1002/cam4.4232
Subject(s) - mycosis fungoides , marital status , medicine , stage (stratigraphy) , epidemiology , population , survival analysis , lymph node , merkel cell carcinoma , demography , oncology , gerontology , carcinoma , lymphoma , biology , paleontology , environmental health , sociology
Background Previous studies have shown that marital status was associated with stages and survival in patients with melanoma or Merkel cell carcinoma. To date, the impacts of marital status on stage and survival in patients with mycosis fungoides (MF) have not been determined yet. Methods A total of 3375 eligible cases diagnosed from 2004 to 2015 were included from the Surveillance, Epidemiology, and End Results (SEER) database. Association of marital status with stage and survival in patients with MF was analyzed. Results Married patients were more likely to be diagnosed at T1 stage ( p = 0.041). And married patients were less likely to present with lymph node involvement ( p = 0.007). More favorable overall survival ( p < 0.001) and cancer‐specific survival ( p < 0.001) were demonstrated in married patients as compared with divorced patients or widowed patients. A clinically feasible prognostic model including marital status, age, sex, race, and stage at presentation was constructed. Conclusion Married marital status was associated with earlier stage at diagnosis and longer survival compared with divorced or widowed marital status in patients with MF.