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Associations of air pollution with peripheral inflammation and cardiac autonomic physiology in children
Author(s) -
Parenteau Anna M.,
Alen Nicholas V.,
La Jennifer,
Luck Alison T.,
Teichrow Devin J.,
Daang Enya M.,
Nissen Adam T.,
Deer LillyBelle K.,
Hostinar Camelia E.
Publication year - 2022
Publication title -
new directions for child and adolescent development
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.628
H-Index - 59
eISSN - 1534-8687
pISSN - 1520-3247
DOI - 10.1002/cad.20474
Subject(s) - inflammation , peripheral , air pollution , psychology , autonomic nervous system , heart rate variability , physiology , developmental psychology , medicine , neuroscience , heart rate , biology , ecology , blood pressure
Climate change‐related disasters have drawn increased attention to the impact of air pollution on health. 122 children ages 9–11 years old, M ( SD ) = 9.91(.56), participated. Levels of particulate matter (PM2.5) near participants’ homes were obtained from the Environmental Protection Agency. Cytokines were assayed from 100 child serum samples: IL‐6, IL‐8, IL‐10, and TNFα. Autonomic physiology was indexed by pre‐ejection period (PEP), respiratory sinus arrhythmia (RSA), cardiac autonomic regulation (CAR), and cardiac autonomic balance (CAB). IL‐6 was positively related to daily PM2.5 ( r = .26, p = .009). IL‐8 was negatively associated with monthly PM2.5 ( r = −.23, p = .02). PEP was positively related to daily ( r = .29, p = .001) and monthly PM2.5 ( r = .18, p = .044). CAR was negatively associated with daily PM2.5 ( r = −.29, p = .001). IL‐10, TNFα, RSA, and CAB were not associated with PM2.5. Air pollution may increase risk of inflammation in children.