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A quantitative ultrastructural study of collagen fibrils in human skin normal scars, and hypertrophic scars
Author(s) -
Stewart K. J.
Publication year - 1995
Publication title -
clinical anatomy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 71
eISSN - 1098-2353
pISSN - 0897-3806
DOI - 10.1002/ca.980080505
Subject(s) - reticular dermis , hypertrophic scar , dermis , collagen fibril , reticular connective tissue , ultrastructure , scars , hypertrophic scars , papillary dermis , medicine , anatomy , fibril , pathology , human skin , electron microscope , biophysics , biology , optics , genetics , physics
The diameter‐distribution of collagen fibrils in the dermis of human skin and scar tissue has been investigated. In samples of normal skin, normal scar, and hypertrophic scar, prepared for transmission electron microscopy, collagen fibrils were systematically random‐sampled and their diameters measured. There was a statistically significant difference between the diameter‐distribution of fibrils in the papillary and reticular layers of dermis in normal skin. A similar pattern was found in normal scar, but not in hypertrophic scar. © 1995 WiIey‐Liss, Inc.