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The effect of testicular biopsy on the regional lymph node of the testis in rats
Author(s) -
McDonald S. W.,
Scothorne R. J.
Publication year - 1988
Publication title -
clinical anatomy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 71
eISSN - 1098-2353
pISSN - 0897-3806
DOI - 10.1002/ca.980010304
Subject(s) - medicine , vasectomy , biopsy , lymph , testicle , pathology , sperm , lymph node , andrology , population , research methodology , environmental health , family planning
Abstract The immunological effects of testicular biopsy are largely unknown. This study on young adult Albino Swiss rats shows no changes in the regional testicular lymph nodes compared to those from sham‐operated controls at either 1 or 3 months after operation. The findings contrast markedly with those of vasectomy after which there are obvious histological changes in the nodes consistent with antisperm antibody formation. The difference is likely to be related to the absence of sperm granulomas or other inflammatory changes in the testis after testicular biopsy.