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Neuroanatomical variation in autism spectrum disorder: A comprehensive review
Author(s) -
Jumah Fareed,
Ghannam Malik,
Jaber Mohammad,
Adeeb Nimer,
Tubbs R. Shane
Publication year - 2016
Publication title -
clinical anatomy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.667
H-Index - 71
eISSN - 1098-2353
pISSN - 0897-3806
DOI - 10.1002/ca.22717
Subject(s) - autism spectrum disorder , medicine , autism , neuroscience , autistic spectrum disorder , broad spectrum , clinical psychology , psychiatry , psychology , chemistry , combinatorial chemistry
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterized by impairments in socialization, communication, and behavior. Many investigators have described the anatomical abnormalities in autistic brains, in an attempt to correlate them with the manifestations of ASD. Herein, we reviewed all the available literature about the neuroanatomical findings in ASD available via “PubMed” and “Google Scholar.” References found in review articles were also searched manually. There was substantial discrepancy throughout the literature regarding the reported presence and significance of neuroanatomical findings in ASD, and this is thoroughly discussed in the present review. Clin. Anat. 29:454–465, 2016. © 2016 Wiley Periodicals, Inc.