Evaluation of Supercritical Fluid Extraction in the Pharmaceutical Industry | Zendy

Larson Karen A. | Zendy; King Michael L. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Evaluation of Supercritical Fluid Extraction in the Pharmaceutical Industry

Author(s) -

Larson Karen A.,

King Michael L.

Publication year - 1986

Publication title -

biotechnology progress

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.572

H-Index - 129

eISSN - 1520-6033

pISSN - 8756-7938

DOI - 10.1002/btpr.5420020206

Subject(s) - supercritical fluid , supercritical fluid extraction , extraction (chemistry) , pharmaceutical industry , chromatography , biochemical engineering , process engineering , chemistry , computer science , microbiology and biotechnology , engineering , organic chemistry , biology

Various steroids precipitate from supercritical CO 2 as very small particles but still retain their crystallinity. This suggests that SCFE in this industry could beutilized as a size reduction method as an alternative to milling. The applicationof SCFE as a separation technique is demonstrated by the simultaneous extraction and reaction of mevinolin, a metabolite of the fungus Aspergillus terreus.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research