Open AccessPrevalence of progressive supranuclear palsy in Yonago: change throughout a decade
Author(s) -
Takigawa Hiroshi,
Kitayama Michio,
WadaIsoe Kenji,
Kowa Hisanori,
Nakashima Kenji
Publication year - 2016
Publication title -
brain and behavior
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.915
H-Index - 41
ISSN - 2162-3279
DOI - 10.1002/brb3.557
Subject(s) - progressive supranuclear palsy , parkinsonism , medicine , demographics , population , confidence interval , epidemiology , pediatrics , disease , demography , environmental health , sociology
Background Progressive supranuclear palsy ( PSP ) is a neurodegenerative disorder that is sometimes confused with Parkinson's disease, multiple system atrophy, and other disorders. The typical clinical features are categorized as Richardson's syndrome ( RS ), but other clinical subtypes include PSP ‐parkinsonism ( PSP ‐P) and PSP ‐pure akinesia with gait freezing ( PSP ‐ PAGF ). In this study, we determined the prevalence of PSP in a Japanese rural area compared to our previous 1999 report. Methods We collected data in Yonago City from 2009 to 2014 using a service‐based study of PSP . We collected case history data from PSP patients in the area from our hospital. The crude prevalence and 95% confidence interval ( CI ) were calculated using the population demographics on the prevalence day of 1 October 2010. Age‐ and sex‐adjusted prevalence was calculated by direct standardization to the population demographics in Yonago City on the prevalence day of 1 April 1999. Material and Results We identified 25 patients: 16 with probable RS , 4 with possible RS , 3 with clinical PSP ‐P, and 2 with clinical PSP ‐ PAGF . The prevalence per 100,000 was 17.90 (male = 18.05; female = 17.76). The prevalence of PSP in Yonago in 2010 increased compared to the measurements from 1999. Conclusion The prevalence of PSP in Japan increased from 1999 to 2010.