Open AccessOptical coherence tomography monitoring and diagnosing retinal changes in multiple sclerosis
Author(s) -
Mehmood Arshad,
Ali Wajid,
Song Shuang,
Din Zaheer Ud,
Guo RuoYi,
Shah Wahid,
Ilahi Ikram,
Yin Bowen,
Yan Hongjing,
Zhang Lu,
Khan Murad,
Ali Wajid,
Zeb Liaqat,
Safari Hamidreza,
Li Bin
Publication year - 2021
Publication title -
brain and behavior
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.915
H-Index - 41
ISSN - 2162-3279
DOI - 10.1002/brb3.2302
Subject(s) - optical coherence tomography , nerve fiber layer , retinal , multiple sclerosis , neurodegeneration , medicine , ganglion , ophthalmology , retina , optic nerve , ganglion cell layer , neuroscience , pathology , anatomy , biology , disease , psychiatry
This study explores the use of optical coherence tomography (OCT) to monitor and diagnose multiple sclerosis (MS). The analysis of reduced total macular volume and peripapillary retinal nerve fiber layer thinning are shown. The severity of these defects increases as MS progresses, reflecting the progressive degeneration of nerve fibers and retinal ganglion cells. The OCT parameters are noninvasive, sensitive indicators that can be used to assess the progression of neurodegeneration and inflammation in MS.