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Dimethyl ether chemical ionization mass spectrometry of trichothecene biotoxins
Author(s) -
Burrows Elizabeth P.
Publication year - 1994
Publication title -
biological mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1052-9306
DOI - 10.1002/bms.1200230806
Subject(s) - adduct , chemistry , mass spectrometry , chemical ionization , trichothecene , reagent , fragmentation (computing) , dissociation (chemistry) , molecule , ether , mass spectrum , ion , ionization , chromatography , organic chemistry , mycotoxin , computer science , operating system , food science
Dimethyl ether (DME) chemical ionization mass spectrometry with introduction by direct exposure desorption has been utilized for the characterization of a group of 23 structurally diverse biologically active trichothecene toxins. Both proton adducts and a variety of fragment‐molecule adduct ions, notably methoxmethylene adducts [M + CH 3 OCH 2 ] + , resulting from ion‐molecule reactions with the reagent gas, were observed. Fragmentation pathways of the proton adducts were documented by collision‐induced dissociation (CID) experiments. CID studies of the prominent methoxymethylene adduct ions were also made and were contrasted with those of the corresponding adducts derived from DME‐ d 6 as reagent gas.