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Transformation of arginine into ornithine during the preparation of its tert ‐butyldimethylsilyl derivative for analysis by gas chromatography/mass spectrometry
Author(s) -
Corso Gaetano,
Esposito Mauro,
Gallo Monica,
Russo Antonio Dello,
Antonio Malorni
Publication year - 1993
Publication title -
biological mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1052-9306
DOI - 10.1002/bms.1200221205
Subject(s) - chemistry , carbodiimide , chromatography , ornithine , mass spectrometry , arginine , gas chromatography , gas chromatography–mass spectrometry , derivative (finance) , derivatization , cleavage (geology) , organic chemistry , amino acid , biochemistry , biology , paleontology , fracture (geology) , financial economics , economics
Abstract The reaction of N ‐methyl‐ N‐tert ‐butyldimethylsilyltrifluoroacetamide with arginine proceeds with cleavage of the guanidino group, producing a mixture of the tert ‐butyldimethylsilyl derivatives of ornithine and carbodiimide. These compounds are identified by analysing the reaction mixture using gas chromatography/mass spectrometry.