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Laser desorption ionization mass spectrometry in the study of natural and synthetic melanins. I—Tyrosine melanins
Author(s) -
Seraglia Roberta,
Traldi Pietro,
Elli Giuseppe,
Bertazzo Antonella,
Costa Carlo,
Allegri Graziella
Publication year - 1993
Publication title -
biological mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1052-9306
DOI - 10.1002/bms.1200221204
Subject(s) - mass spectrometry , desorption , chemistry , ionization , tyrosine , analytical chemistry (journal) , laser , chromatography , organic chemistry , ion , optics , biochemistry , physics , adsorption
Nine synthetic, biosynthetic and natural tyrosine melanins, together with dopa and catechol melanins, have been studied by means of laser desorption ionization mass spectrometry. The results obtained have shown that all the melanins under study consist of homogeneous sets of oligomers and have led to definitive information on their molecular weight distribution (from 500 to 30000 Da). A deeper analysis of the spectra, in terms of mass differences among the various oligomers, allowed the identification of some monomeric units, identical or analogous to those already proposed in the literature.