Premium
Differential electron capture mass spectral response of pentafluorobenzoyl derivatives of platelet activating factor alkyl chain homologs
Author(s) -
Weintraub Susan T.,
Lear Cynthia,
Pinckard R. Neal
Publication year - 1993
Publication title -
biological mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1052-9306
DOI - 10.1002/bms.1200221002
Subject(s) - alkyl , chemistry , platelet , gas chromatography , chain (unit) , chromatography , homologous series , platelet activating factor , analytical chemistry (journal) , organic chemistry , biology , immunology , physics , astronomy
The electron capture mass spectrometric response of pentafluorobenzoyl ester derivatives of platelet‐activating factor alkyl chain homologs has been found to be inversely proportional to their alkyl chain length. This phenomenon was observed when either the gas chromatograph or direct insertion probe was utilized for sample introduction. A similar differential response was also obtained for a series of fatty alcohols, analyzed as pentafluorobenzoyl esters. These studies demonstrate that multiple standard curves must be prepared for analysis of platelet‐activating factor and related lipids in order to obtain accurate quantification.