On‐line high‐performance liquid chromatographic/gas chromatographic/tandem ion trap mass spectrometric determination of levamisole in milk | Zendy

Chappell Colin G. | Zendy; Creaser Colin S. | Zendy; Stygall James W. | Zendy; Shepherd Martin J. | Zendy

Premium

On‐line high‐performance liquid chromatographic/gas chromatographic/tandem ion trap mass spectrometric determination of levamisole in milk

Author(s) -

Chappell Colin G.,

Creaser Colin S.,

Stygall James W.,

Shepherd Martin J.

Publication year - 1992

Publication title -

biological mass spectrometry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 121

eISSN - 1096-9888

pISSN - 1052-9306

DOI - 10.1002/bms.1200211211

Subject(s) - chromatography , chemistry , mass spectrometry , ion trap , tandem mass spectrometry , quadrupole ion trap , gas chromatography , mass spectrum , analytical chemistry (journal) , levamisole , extraction (chemistry) , resolution (logic) , tandem , electron ionization , detection limit , ion , ionization , materials science , medicine , organic chemistry , artificial intelligence , computer science , composite material

On‐line high‐performance liquid chromatography/high‐resolution gas chromatography/tandem mass spectrometry, performed on a quadrupole ion trap, has been used as a rapid method for the quantification of the anthelmintic drug levamisole in raw milk extracts following a simple extraction procedure. Detection at the 0.5 p.p.b. level and a linear response in the 10‐0.5 p.p.b. range is demonstrated. Multiple‐scan monitoring techniques have been used to acquire chemical ionization tandem mass spectra and electron impact mass spectra in a single chromatographic run.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research