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Thermospray liquid chromatography/mass spectrometry of polar β‐blocking drugs: Preliminary results
Author(s) -
Leloux M. S.,
Niessen W. M. A.,
van der Hoeven R. A. M.
Publication year - 1991
Publication title -
biological mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1052-9306
DOI - 10.1002/bms.1200201010
Subject(s) - thermospray , blocking (statistics) , polar , chromatography , mass spectrometry , chemistry , liquid chromatography–mass spectrometry , tandem mass spectrometry , computer science , physics , selected reaction monitoring , astronomy , computer network
The use of thermospray liquid chromatography for the screening of polar β‐blocking drugs is evaluated. The influence of instrumental parameters on the fragmentation pattern of labetalol, acebutolol, diacetolol, sotalol and atenolol is described. A short biomedical application is presented.