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The development of a gas chromatographic/mass spectrometric screening procedure to detect the administration of anabolic steroids to the horse
Author(s) -
Teale P.,
Houghton E.
Publication year - 1991
Publication title -
biological mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 1052-9306
DOI - 10.1002/bms.1200200303
Subject(s) - chromatography , anabolism , chemistry , anabolic steroid , urine , gas chromatography–mass spectrometry , gas chromatography , mass spectrometry , biochemistry
A screening procedure for anabolic steroid residues in horse urine has been developed based upon solid‐phase extraction and gas chromatographic/mass spectrometric analysis in the selected ion mode. For moderate sample throughput the method provides a viable alternative to radioimmunoassay screening and has advantages over the latter technique due to its flexibility, specificity and ability to detect a number of steroids in a single analysis. Full automation of the gas chromatographic/mass spectrometric analysis is an additional feature of the methodology.