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Fast atom bombardment mass spectrometric analysis of arginine‐containing neuropeptides
Author(s) -
Silberring Jerzy,
Nyberg Fred
Publication year - 1990
Publication title -
biomedical and environmental mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0887-6134
DOI - 10.1002/bms.1200191305
Subject(s) - fast atom bombardment , arginine , neuropeptide , mass spectrometry , chemistry , peptide , biochemistry , chromatography , amino acid , receptor
A new procedure using fast atom bombardment mass spectrometry for the determination of arginine residues in neuropeptides is described. The technique is based on the modification of the arginine side‐group with 1,2‐cyclohexanedione. This novel procedure may have a potential use in the study of neuropeptides and their processing and degrading enzymes.