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Determination of Senecio Alkaloids by thermospray liquid chromatography/mass spectrometry
Author(s) -
Parker C. E.,
Verma S.,
Tomer K. B.,
Reed R. L.,
Buhler D. R.
Publication year - 1990
Publication title -
biomedical and environmental mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0887-6134
DOI - 10.1002/bms.1200190102
Subject(s) - thermospray , pyrrolizidine , chemistry , alkaloid , senecio , chromatography , ammonium hydroxide , ammonium acetate , mass spectrometry , ammonium , liquid chromatography–mass spectrometry , tetramethylammonium hydroxide , high performance liquid chromatography , botany , organic chemistry , stereochemistry , tandem mass spectrometry , biology , selected reaction monitoring
A series of Senecio alkaloid and alkaloid N ‐oxide standards has been analyzed using positive and negative ion thermospray liquid chromatography/mass spectrometry (LC/MS) with an ammonium acetate‐containing mobile phase. On‐line separations of pyrrolizidine alkaloids from extracts of Senecio jacobaea (tansy ragwort) and Senecio vulgaris (common groundsel) were done using an ammonium hydroxide‐containing mobile phase. All of the alkaloids known to be present in the extracts were detected by ammonium hydroxide thermospray LC/MS, as well as many other components which may be as‐yet‐unidentified alkaloids.