Premium
Deuterium‐labeled 3‐nitrobenzyl alcohol as a matrix for fast atom bombardment mass spectrometry 1
Author(s) -
Reddy A. Mahender,
Mykytyn Victoria V.,
Schram Karl H.
Publication year - 1989
Publication title -
biomedical and environmental mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0887-6134
DOI - 10.1002/bms.1200181209
Subject(s) - deuterium , chemistry , matrix (chemical analysis) , alcohol , molecule , fast atom bombardment , atom (system on chip) , glycerol , mass spectrometry , crystallography , organic chemistry , chromatography , physics , atomic physics , computer science , embedded system
The utility of deuterium‐labeled 3‐nitrobenzyl alcohol (DNBA) as a fast atom bombardment (FAB) matrix for establishing the number of exchangeable hydrogens present in a molecule is illustrated by the analysis of five selected antitumor agents. A method for the simple preparation of this labeled matrix is described. The use of DNBA may be of value for samples which provide no FAB spectra when deuterium‐labeled glycerol is used as a matrix.