Premium
On‐line negative ion liquid chromatography/mass spectrometry for the analysis of bile acids using low‐ and high‐resolution mass spetrometry
Author(s) -
Eckers Christine,
Haskins Neville J.,
Large Tom
Publication year - 1989
Publication title -
biomedical and environmental mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0887-6134
DOI - 10.1002/bms.1200180909
Subject(s) - chromatography , mass spectrometry , resolution (logic) , chemistry , analytical chemistry (journal) , polyethylene glycol , ion , organic chemistry , artificial intelligence , computer science
Abstract Liquid chromatographic/mass spectrometric analysis of a mixture of bile acids has been carried out using a double‐focusing mass spectrometer. A solution of polyethylene glycol was added post‐column using a second pump and a micro vortex mixer. The mass spectrometer was tuned to give a 10 000 resolution, and mass measurement accuracies of greater than 3 mmu were obtained on‐line.