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Capillary supercritical fluid chromatography/negative ion chemical ionization mass spectrometry of trichothecenes
Author(s) -
Roach John A. G.,
Sphon James A.,
Easterling James A.,
Calvey Elizabeth M.
Publication year - 1989
Publication title -
biomedical and environmental mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0887-6134
DOI - 10.1002/bms.1200180109
Subject(s) - chemistry , mass spectrometry , chromatography , chemical ionization , supercritical fluid chromatography , analytical chemistry (journal) , capillary action , supercritical fluid , mass spectrum , ion , gas chromatography , ionization , organic chemistry , materials science , composite material
A capillary supercritical fluid chromatography/mass spectrometry interface incorporating a heated frit restrictor is described. The trichothecene mycotoxins T‐2 toxin, deoxynivalenol and roridin A were used to evaluate the effect of restrictor temperature and carbon dioxide mobile phase on the negative ion chemical ionization (CI) spectra of these compounds under electron capture, proton abstraction and chloride attachment conditions. Restrictor temperatures less than 100°C above the melting point of the samples retarded sample transfer into the mass spectrometer, but neither restrictor temperature nor carbon dioxide mobile phase significantly affected negative ion CI conditions.