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Mass spectrometric investigation of the temperature dependence of gas transport through a human body to the lungs
Author(s) -
Adamczyk B.,
Boerboom A. J. H.,
Kistemaker J.
Publication year - 1988
Publication title -
biomedical and environmental mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0887-6134
DOI - 10.1002/bms.1200160190
Subject(s) - humidity , helium , relative humidity , chemistry , analytical chemistry (journal) , mass spectrometry , warm front , thermodynamics , chromatography , meteorology , physics , organic chemistry
This paper shows the results of the experiment on gas dynamic transport of helium from outside through the skin to the lungs of man in conditions of changing temperature and humidity of surroundings. The apparatus includes: an elastic bag in which the whole subject can be saturated by helium; a heating and refrigerating system; a respiratory system; an introduction system to the mass spectrometer; and a mass spectrometer with an ion detector of high sensitivity. The temperature of the surroundings varied from 24°C up to 44°C and humidity varied from 50% up to 95%. The temperature of skin varied from 25°C up to 37°C. Also the temperature oscillations of the period from 1 to 3 min were generated. In effect, those oscillations corresponded with the oscillations of He concentration in the expired air. At the higher level of humidity of the surroundings, a higher concentration of helium in the expired air was observed. At 100% He concentration in the bag, the minimal He concentration in the expired air was 40 ppm and maximal 110 ppm. In the opinion of the authors the thermoregulation system in the body of the subject played a significant role in the observed process of gas transport.