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Tandem mass spectrometry in vitamin E analysis
Author(s) -
Walton Terence J.,
Mullins Carol J.,
Newton Russell P.,
Brenton A. Gareth,
Bey John H.
Publication year - 1988
Publication title -
biomedical and environmental mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0887-6134
DOI - 10.1002/bms.1200160156
Subject(s) - mass spectrometry , tandem mass spectrometry , collision induced dissociation , chemistry , ion , kinetic energy , electron ionization , mass spectrum , dissociation (chemistry) , analytical chemistry (journal) , ionization , tandem , chemical ionization , chromatography , materials science , organic chemistry , physics , quantum mechanics , composite material
Tandem mass spectrometry is applied to the tocopherols and representative tocotrienols of the vitamin E family. The collision‐induced dissociation/mass analysed ion kinetic energy spectra generated from three ions in the electron impact ionization spectra of 5,7,8‐trimethyltocol, 5,7,8‐trimethyltocotrienol, 5,7‐, 5,8‐ and 7,8‐dimethyltocol and 7,8‐dimethyltocotrienol are described. The technique allowed direct physical characterization of each class of tocochromanol, and in the case of monomethyltocols differentiation of 5‐methyltocol from the 7‐ and 8‐methyltocol isomers, and its value in analysis of biological tissue extracts is established.