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A selected ion monitoring assay for triclosan in medical waste water
Author(s) -
Matsushima Hajime
Publication year - 1988
Publication title -
biomedical and environmental mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0887-6134
DOI - 10.1002/bms.1200160148
Subject(s) - triclosan , trimethylsilyl , elution , chromatography , chemistry , ethyl acetate , wastewater , waste management , organic chemistry , medicine , pathology , engineering
A method for determinations of triclosan (TCS) and hexachlorophene (HCP) disinfectants in medical waste water by selected ion monitoring (SIM) using bithionol (BTN) as an internal standard compound has been developed. The method consists of the following procedures. (i) TCS and HCP in medical waste water were extracted and purified by an Extrelut® column with ethyl acetate. (ii) The eluted TCS, HCP and BTN were converted to trimethylsilyl (TMS) derivatives with N,O ‐bis(trimethylsilyl)trifluoroacetamide‐ethyl acetate (1:4). (iii) The TMS derivatives of TCS, HCP and BTN were identified and determined by SIM. Recoveries of these compounds added to medical waste water were more than 88% in amounts ranging from 1 to 10 μg. In the waters from our medical waste water treatment plant, TCS and HCP concentrations were found to be 0.43–8.01 and 0.24–4.69 μg 1 −1 , respectively. The present method is superior to the pre‐existing ones in quick separation, specificity and sensitivity.