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Characterization of trichothecenes by tandem mass spectrometry using reactive collisions with ammonia
Author(s) -
Kostiainen R.
Publication year - 1988
Publication title -
biomedical and environmental mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0887-6134
DOI - 10.1002/bms.1200160135
Subject(s) - chemistry , ammonia , mass spectrometry , adduct , protonation , ion , dissociation (chemistry) , tandem mass spectrometry , ammonium , molecule , selected reaction monitoring , analytical chemistry (journal) , chromatography , organic chemistry
The use of low‐energy (7 eV lab ) reactive collisions with ammonia provides a highly specific method for the characterization of trichothecenes since the collisions between the protonated molecule and ammonia not only produce ions formed by collisionally activated dissociation but ammonium adduct ions and ions formed by substitution reactions. The good detection limits (20–300 pg) and good quantitative reproducibility (relative standard deviations are 5–10%) mean that the use of reactive collisions with ammonia is also very suitable for monitoring and quantitative analyses.