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Laser‐desorption/laser‐ionization mass spectrometry of biomolecules 1
Author(s) -
Grotemeyer J.,
Schlag E. W.
Publication year - 1988
Publication title -
biomedical and environmental mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0887-6134
DOI - 10.1002/bms.1200160125
Subject(s) - atmospheric pressure laser ionization , mass spectrometry , ionization , matrix assisted laser desorption electrospray ionization , laser , soft laser desorption , mass spectrum , ion source , chemistry , polyatomic ion , ambient ionization , ion , atomic physics , molecular beam , evaporation , yield (engineering) , chemical ionization , desorption , photoionization , molecule , materials science , electron ionization , optics , matrix assisted laser desorption/ionization , physics , chromatography , organic chemistry , adsorption , metallurgy , thermodynamics
Some applications of the powerful novel method of laser evaporation of intact neutral molecules into a supersonic beam and the subsequent multiphoton ionization are shown. The mass spectra of several bioorganic molecules are presented and their intrinsic features upon the multiphoton interaction are discussed. Owing to the details of desorption and multiphoton ionization these mass spectra yield, in relation to the intensity of the laser beam, in very few and structural dependent signals. In every case the molecular ion of the investigated sample is detected.