Identification of metabolites of tiropramide in human urine | Zendy

Arigoni R. | Zendy; Chistè R. | Zendy; Makovec F. | Zendy; Setnikar I. | Zendy; Benfenati E. | Zendy; Fanelli R. | Zendy

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Identification of metabolites of tiropramide in human urine

Author(s) -

Arigoni R.,

Chistè R.,

Makovec F.,

Setnikar I.,

Benfenati E.,

Fanelli R.

Publication year - 1988

Publication title -

biomedical and environmental mass spectrometry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 121

eISSN - 1096-9888

pISSN - 0887-6134

DOI - 10.1002/bms.1200150404

Subject(s) - urine , chromatography , mass spectrum , mass spectrometry , hydrochloride , gas chromatography–mass spectrometry , chemistry , gas chromatography , identification (biology) , biology , organic chemistry , biochemistry , botany

The metabolites of tiropramide were extracted from the urine of healthy volunteers given tiropramide hydrochloride orally. Eight metabolites of tiropramide were found by gas chromatography/mass spectrometry. Three were identified on the basis of their mass spectra, retention times and comparison with synthetic standards. For the others a probable structure is proposed on the basis of their mass spectra.

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