Abnormal  n ‐nonacosane storage in humans: Detection by gas chromatography/mass spectrometry of tissue extracts | Zendy

Rocchiccioli Francis | Zendy; Lageron Alice | Zendy; Duboucher Christophe | Zendy

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Abnormal n ‐nonacosane storage in humans: Detection by gas chromatography/mass spectrometry of tissue extracts

Author(s) -

Rocchiccioli Francis,

Lageron Alice,

Duboucher Christophe

Publication year - 1987

Publication title -

biomedical and environmental mass spectrometry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 121

eISSN - 1096-9888

pISSN - 0887-6134

DOI - 10.1002/bms.1200140902

Subject(s) - chromatography , mass spectrometry , gas chromatography–mass spectrometry , gas chromatography , chemistry

We report a case of n ‐nonacosane storage disease, which went undiagnosed until the death of a 55‐year‐old farmer. Clinical, histological, and biochemical features are discussed. n ‐Nonacosane storage was identified by gas chromato‐graphic‐mass spectrometric analysis of different tissue extracts, n ‐nonacosane concentration reaching 1.2 mg g −1 of lung tissue and 0.32 mg g −1 of liver tissue. It was possible to rule out a work‐induced intoxication, and n ‐nonacosane storage appeared to be accounted for by a lifelong, heavy consumption of unpeeled apples and Brussels sprouts.

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